{"id":5257,"date":"2024-12-11T17:24:43","date_gmt":"2024-12-11T16:24:43","guid":{"rendered":"https:\/\/irccs.com\/patologie\/uterine-fibroids\/"},"modified":"2026-03-30T09:41:31","modified_gmt":"2026-03-30T07:41:31","slug":"uterine-fibroids","status":"publish","type":"pathology","link":"https:\/\/irccs.com\/en\/pathology\/uterine-fibroids\/","title":{"rendered":"Uterine fibroids"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><span  id=\"pathology\" class=\"h2_anchor\"><\/span>Pathology<\/h2>\n\n\n\n<p><strong>Uterine myomas<\/strong>, also called <strong>leiomyomas<\/strong> or <strong>fibroids<\/strong>, are <strong>benign tumors<\/strong> that develop in the smooth muscle of the uterus. They are characterized by hyperdevelopment of smooth muscle cells and connective tissue of the uterus.<\/p>\n\n\n\n<p>Their <strong>incidence<\/strong> varies between <strong>20-25% and 40%<\/strong> in women of childbearing age, with differences related to factors such as <strong>ethnicity<\/strong> and <strong>family history<\/strong>.<\/p>\n\n\n\n<p>The possibility of a <strong>benign uterine myoma<\/strong> mimicking a <strong>uterine sarcoma<\/strong> is <strong>extremely rare<\/strong>, estimated to be around <strong>0.03%<\/strong>. <strong>Uterine sarcoma<\/strong> is a rare malignancy that accounts for about <strong>7% of all uterine malignancies<\/strong>.<\/p>\n\n\n\n<p>In most cases, with the arrival of <strong>menopause<\/strong> and the consequent <strong>reduction in hormone levels<\/strong>, <strong>uterine myomas<\/strong> tend to <strong>shrink in size<\/strong>, resulting in <strong>alleviation or disappearance of symptoms<\/strong>.<\/p>\n\n\n\n<p>The Candiolo Institute is involved in the <strong>diagnosis and treatment<\/strong> of this disease, with a focus on two key aspects: understanding whether there is a risk that the disease may evolve into malignancy and recognizing atypical forms early, which require early intervention.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Types<\/h3>\n\n\n\n<p>Fibroids can have different localizations in the uterus:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>&#8220;<strong>Subserous<\/strong>&#8221; myoma, develops outside the uterus;<\/li>\n\n\n\n<li>&#8220;<strong>submucosal<\/strong>&#8221; myoma, develops within the uterine cavity;<\/li>\n\n\n\n<li>&#8220;<strong>intramural<\/strong>&#8221; myoma; develops within the uterine muscle (myometrium).<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span  id=\"symptoms\" class=\"h2_anchor\"><\/span>Symptoms<\/h2>\n\n\n\n<p>In some cases uterine myomas are <strong>asymptomatic.<\/strong> In others, depending on their size, number and location, symptoms may manifest with:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Abdominal, sacral or lumbar pain<\/strong>;<\/li>\n\n\n\n<li><strong>abdominal bloating<\/strong>;<\/li>\n\n\n\n<li><strong>sense of pelvic weight<\/strong>;<\/li>\n\n\n\n<li><strong>constipation<\/strong>;<\/li>\n\n\n\n<li><strong>urination disorders.<\/strong><\/li>\n<\/ul>\n\n\n\n<p>It should also be pointed out that some uterine fibroids, some submucosal ones, can cause <strong>severe genital bleeding <\/strong>as well as <strong>infertility<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span  id=\"risk-factors\" class=\"h2_anchor\"><\/span>Risk factors<\/h2>\n\n\n\n<p>Risk factors for <strong>uterine myomas<\/strong> include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Age:<\/strong> most common between the ages of 40 and 50;<\/li>\n\n\n\n<li><strong>Familiarity:<\/strong> increased risk if the mother had fibroids;<\/li>\n\n\n\n<li><strong>ethnicity:<\/strong> more frequent in African American women;<\/li>\n\n\n\n<li><strong>Obesity: <\/strong>high body mass index increases risk;<\/li>\n\n\n\n<li><strong>Early menarche:<\/strong> onset of menstruation before age 10;<\/li>\n\n\n\n<li><strong>nulliparity:<\/strong> absence of pregnancy;<\/li>\n\n\n\n<li><strong>Alcohol: <\/strong>excessive consumption may increase risk;<\/li>\n\n\n\n<li><strong>Diet: <\/strong>high consumption of red meat and high-fat dairy products;<\/li>\n\n\n\n<li><strong>Chronic stress:<\/strong> may contribute to the development of myomas.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span  id=\"diagnosis-and-examination\" class=\"h2_anchor\"><\/span>Diagnosis and examination<\/h2>\n\n\n\n<p><strong>Uterine myomas<\/strong> are often discovered <strong>incidentally<\/strong> during a routine <a href=\"https:\/\/irccs.com\/en\/divisioni-cliniche\/gynecologic-oncology-and-hereditary-tumors\/\" type=\"medical-area\" id=\"5119\">gynecologic examination<\/a><a href=\"https:\/\/irccs.com\/aree-mediche\/ginecologia-oncologica\/\"> <\/a>.<\/p>\n\n\n\n<p>For an <strong>accurate diagnosis<\/strong> they are critical:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Detailed medical history<\/strong>, collecting the patient&#8217;s symptoms and needs;<\/li>\n\n\n\n<li><strong>Gynecological objective examination<\/strong>;<\/li>\n\n\n\n<li><strong>Pelvic ultrasonography<\/strong>, transvaginal and transabdominal, which allows <strong>localization of myomas<\/strong> and evaluation of their ultrasonographic characteristics.<\/li>\n<\/ul>\n\n\n\n<p>In some cases it may be useful to perform a<strong>diagnostic hysteroscopy<\/strong>, a minimally invasive, rapid examination that can be performed without anesthesia and allows <strong>direct observation of the uterine cavity<\/strong>.<\/p>\n\n\n\n<p>If clinical or ultrasonographic features are not typical and <strong>malignant degeneration<\/strong> is suspected, the specialist may request further investigation by <strong>Nuclear Magnetic Resonance Imaging (MRI<\/strong>).<\/p>\n\n\n\n<p>Myomas must be distinguished from other conditions, such as<strong>adenomyosis<\/strong> (<a href=\"https:\/\/irccs.com\/en\/patologie\/endometriosis\/\" type=\"pathology\" id=\"5248\">endometriosis of the uterus<\/a>) or other uterine masses, including <strong>sarcomas<\/strong>, which are otherwise very rare; the definite diagnosis of sarcomas is usually made by <strong>histologic analysis after surgery.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span  id=\"therapies\" class=\"h2_anchor\"><\/span>Therapies<\/h2>\n\n\n\n<p>In cases of <strong>small asymptomatic myomas<\/strong>, <strong>periodic clinical and instrumental monitoring<\/strong> to control their size and characteristics is sufficient.<\/p>\n\n\n\n<p>When fibroids become <strong>symptomatic<\/strong> or reach significant size, treatment options include:<\/p>\n\n\n\t<div id=\"block_69c677a778f95\" class=\"accordion-block acf-block\">\n\t\t<div class=\"my-4 lg:my-6\">\n\t\t\t<div class=\"accordion group border-b border-white\/5\">\n\t\t\t<div class=\"flex items-center cursor-pointer group-hover:text-blue-light group-[.accordion--open]:text-red transition-colors\">\n\t\t\t\t<div class=\"rotate-90 text-blue-lighter group-[.accordion--open]:rotate-180 group-[.accordion--open]:text-red transition-all\">\n\t\t\t\t\t<svg width=\"18\" viewbox=\"0 0 500 500\" fill=\"currentColor\">\n\t\t\t\t\t\t<polygon points=\"250,60 100,400 400,400\"\/>\n\t\t\t\t\t<\/svg>\n\t\t\t\t<\/div>\n\t\t\t\t<h3 class=\"font-bold ml-5\">Surgical therapy<\/h3>\n\t\t\t<\/div>\n\t\t\t<div class=\"accordion-content max-h-0 overflow-hidden transition-all\">\n\t\t\t\t<div class=\"pb-5 pl-[38px] pt-1\">\n\t\t\t\t\t<p>Surgical treatment is indicated in more complex cases or when medication is not sufficient.<\/p>\n<p>It consists of the<strong>removal of the myoma<\/strong> (myomectomy) and can be performed <strong>hysteroscopically<\/strong> or more frequently <strong>laparotomically<\/strong>, depending on location, size, number of fibroids, age of the patient, and her reproductive desire.<\/p>\n<p><!-- \/wp:paragraph --> <!-- wp:paragraph --><\/p>\n<p>In case the patient has exhausted her reproductive desire, prophylactic uterine and tubal removal surgery (hysterectomy and salpingectomy\/annexectomy) can be performed, which can be done laparoscopically or laparotomically depending on the patient&#8217;s medical history and the size of the uterus.<\/p>\n<p><!-- \/wp:paragraph --> <!-- wp:paragraph --><\/p>\n<p>In selected cases,<strong>uterine artery embolization <\/strong>can be performed, a minimally invasive procedure that selectively occludes the blood vessels supplying the uterus with embolizing substances under radiological control and regresses ischemic-based myomas.<\/p>\n\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<div class=\"accordion group border-b border-white\/5\">\n\t\t\t<div class=\"flex items-center cursor-pointer group-hover:text-blue-light group-[.accordion--open]:text-red transition-colors\">\n\t\t\t\t<div class=\"rotate-90 text-blue-lighter group-[.accordion--open]:rotate-180 group-[.accordion--open]:text-red transition-all\">\n\t\t\t\t\t<svg width=\"18\" viewbox=\"0 0 500 500\" fill=\"currentColor\">\n\t\t\t\t\t\t<polygon points=\"250,60 100,400 400,400\"\/>\n\t\t\t\t\t<\/svg>\n\t\t\t\t<\/div>\n\t\t\t\t<h3 class=\"font-bold ml-5\">Drug therapy<\/h3>\n\t\t\t<\/div>\n\t\t\t<div class=\"accordion-content max-h-0 overflow-hidden transition-all\">\n\t\t\t\t<div class=\"pb-5 pl-[38px] pt-1\">\n\t\t\t\t\t<p>It is mainly used to <strong>reduce anemia<\/strong> caused by profuse bleeding or <strong>prepare the patient for possible surgery.<\/strong><\/p>\n<p><strong data-start=\"215\" data-end=\"263\">Drugs for the treatment of uterine myomas<\/strong> include:<\/p>\n<ul>\n<li data-start=\"278\" data-end=\"464\">\n<p data-start=\"280\" data-end=\"325\"><strong data-start=\"280\" data-end=\"323\">Combined hormonal contraceptives (COCs):<\/strong><\/p>\n<ul data-start=\"328\" data-end=\"464\">\n<li data-start=\"328\" data-end=\"380\">\n<p data-start=\"330\" data-end=\"380\">Oral, vaginal or transdermal administration;<\/p>\n<\/li>\n<li data-start=\"383\" data-end=\"464\">\n<p data-start=\"385\" data-end=\"464\">help regulate the menstrual cycle and reduce profuse bleeding.<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"466\" data-end=\"680\">\n<p data-start=\"468\" data-end=\"492\"><strong data-start=\"468\" data-end=\"490\">Estro-progestins:<\/strong><\/p>\n<ul data-start=\"495\" data-end=\"680\">\n<li data-start=\"495\" data-end=\"534\">\n<p data-start=\"497\" data-end=\"534\">They combine estrogen and progestin;<\/p>\n<\/li>\n<li data-start=\"537\" data-end=\"603\">\n<p data-start=\"539\" data-end=\"603\">can be taken orally, vaginally or transdermally;<\/p>\n<\/li>\n<li data-start=\"606\" data-end=\"680\">\n<p data-start=\"608\" data-end=\"680\">serve to control menstrual symptoms and excessive bleeding.<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"682\" data-end=\"858\">\n<p data-start=\"684\" data-end=\"702\"><strong data-start=\"684\" data-end=\"700\">Progestins:<\/strong><\/p>\n<ul data-start=\"705\" data-end=\"858\">\n<li data-start=\"705\" data-end=\"799\">\n<p data-start=\"707\" data-end=\"799\">Available in oral, intrauterine (slow-release coil) or subcutaneous formulations;<\/p>\n<\/li>\n<li data-start=\"802\" data-end=\"858\">\n<p data-start=\"804\" data-end=\"858\">Can reduce bleeding and pelvic pain.<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"860\" data-end=\"1190\">\n<p data-start=\"862\" data-end=\"885\"><strong data-start=\"862\" data-end=\"883\">GnRH analogues:<\/strong><\/p>\n<ul data-start=\"888\" data-end=\"1190\">\n<li data-start=\"888\" data-end=\"941\">\n<p data-start=\"890\" data-end=\"941\">Inhibit the gonadotropic activity of the pituitary gland;<\/p>\n<\/li>\n<li data-start=\"944\" data-end=\"1062\">\n<p data-start=\"946\" data-end=\"1062\">temporarily suppress ovarian hormone production, creating a reversible state of <strong data-start=\"1039\" data-end=\"1059\">pseudo-menopause<\/strong>;<\/p>\n<\/li>\n<li data-start=\"1065\" data-end=\"1190\">\n<p data-start=\"1067\" data-end=\"1190\">mainly used to reduce the size of myomas before surgery or to manage severe symptoms.<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul class=\"wp-block-list\"><!-- \/wp:list-item --><\/ul>\n\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n\t<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span  id=\"interdisciplinary-group\" class=\"h2_anchor\"><\/span>Interdisciplinary Group<\/h2>\n\n\n\n<p>Every cancer requires, in all phases of disease management, a<strong> multidisciplinary approach<\/strong> that at the Candiolo Institute is guaranteed by a team of different specialists, belonging to the various clinical and surgical departments of the Institute: this team is called GIC (Interdisciplinary Care Group). The GIC ensures that<strong> each patient is taken care of throughout the diagnostic-therapeutic process<\/strong>, including prescribing and booking examinations and communicating with the patient and his or her family members. The GIC defines and shares a <strong>personalized care pathway<\/strong> for each patient, based not only on the type and stage of the tumor, but also on the patient&#8217;s own characteristics. The goal is to ensure that he or she has the best outcome both oncologically and functionally and the maintenance of a good quality of life.The Group also<strong> works closely with researchers<\/strong> at the Institute to ensure that patients have rapid access to the latest research-produced innovations in screening, diagnosis and treatment.<\/p>\n\n\n\n<p>Regarding <strong>uterine myomas <\/strong>, the referral GIC is the <strong>GINECOLOGICAL TUMORS GIC<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span  id=\"clinical-divisions\" class=\"h2_anchor\"><\/span>Clinical divisions  <\/h2>\n\n\n\n<p>The diagnostic-therapeutic pathway for uterine fibroids at Candiolo involves several clinical divisions, including:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/irccs.com\/en\/divisioni-cliniche\/ovarian-cancer-center\/\" type=\"medical-area\" id=\"5148\">Ovarian Cancer Center<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/irccs.com\/en\/divisioni-cliniche\/gynecologic-oncology-and-hereditary-tumors\/\" type=\"medical-area\" id=\"5119\">Gynecologic oncology<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/irccs.com\/en\/divisioni-cliniche\/anesthesia-and-resuscitation\/\" type=\"medical-area\" id=\"5185\">Anesthesia and resuscitation<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/irccs.com\/en\/divisioni-cliniche\/nuclear-medicine\/\" type=\"medical-area\" id=\"5106\">Nuclear medicine<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/irccs.com\/en\/divisioni-cliniche\/radiotherapy\/\" type=\"medical-area\" id=\"5104\">Radiotherapy<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/irccs.com\/en\/divisioni-cliniche\/radiodiagnostics\/\" type=\"medical-area\" id=\"5101\">Radiodiagnostics<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/irccs.com\/en\/divisioni-cliniche\/pathologic-anatomy\/\" type=\"medical-area\" id=\"5118\">Pathologic anatomy<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span  id=\"clinical-studies\" class=\"h2_anchor\"><\/span>Clinical studies<\/h2>\n\n\n\n<p>Researchers at the Candiolo Institute are currently involved in<strong> several national and international projects on gynecological diseases.<\/strong> <\/p>\n\n\n\n<p>The main ones involve clinical research and ultrasound diagnosis,<strong> early detection of uterine sarcomas and their differentiation from myomas<\/strong>. Pharmacological and hormone therapy studies are also underway.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span  id=\"why-choose-us\" class=\"h2_anchor\"><\/span>Why choose us<\/h2>\n\n\n\n<p>At the Candiolo IRCCS Institute, each patient is<strong> followed according to highly specialized standards, <\/strong>thanks to the synergistic work of a dedicated <a href=\"#gruppo-interdisciplinare\">Interdisciplinary Care Group (ICG) <\/a>.<\/p>\n\n\n\t<div id=\"block_69c677a779016\" class=\"accordion-block acf-block\">\n\t\t<div class=\"my-4 lg:my-6\">\n\t\t\t<div class=\"accordion group border-b border-white\/5\">\n\t\t\t<div class=\"flex items-center cursor-pointer group-hover:text-blue-light group-[.accordion--open]:text-red transition-colors\">\n\t\t\t\t<div class=\"rotate-90 text-blue-lighter group-[.accordion--open]:rotate-180 group-[.accordion--open]:text-red transition-all\">\n\t\t\t\t\t<svg width=\"18\" viewbox=\"0 0 500 500\" fill=\"currentColor\">\n\t\t\t\t\t\t<polygon points=\"250,60 100,400 400,400\"\/>\n\t\t\t\t\t<\/svg>\n\t\t\t\t<\/div>\n\t\t\t\t<h3 class=\"font-bold ml-5\">Clinical experience and tailored approach<\/h3>\n\t\t\t<\/div>\n\t\t\t<div class=\"accordion-content max-h-0 overflow-hidden transition-all\">\n\t\t\t\t<div class=\"pb-5 pl-[38px] pt-1\">\n\t\t\t\t\t<p>Due to the high number of cases treated each year, the Candiolo Institute is a <strong>national reference for taking care of esophageal cancer.<\/strong> Our experience enables us to deal with even the most complex situations, always with a <strong>personalized approach<\/strong> built on the clinical and personal profile of each patient.<\/p>\n\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<div class=\"accordion group border-b border-white\/5\">\n\t\t\t<div class=\"flex items-center cursor-pointer group-hover:text-blue-light group-[.accordion--open]:text-red transition-colors\">\n\t\t\t\t<div class=\"rotate-90 text-blue-lighter group-[.accordion--open]:rotate-180 group-[.accordion--open]:text-red transition-all\">\n\t\t\t\t\t<svg width=\"18\" viewbox=\"0 0 500 500\" fill=\"currentColor\">\n\t\t\t\t\t\t<polygon points=\"250,60 100,400 400,400\"\/>\n\t\t\t\t\t<\/svg>\n\t\t\t\t<\/div>\n\t\t\t\t<h3 class=\"font-bold ml-5\">Imaging technologies and advanced diagnostics<\/h3>\n\t\t\t<\/div>\n\t\t\t<div class=\"accordion-content max-h-0 overflow-hidden transition-all\">\n\t\t\t\t<div class=\"pb-5 pl-[38px] pt-1\">\n\t\t\t\t\t<p><!-- wp:paragraph -->Establishing the treatment plan always starts with an <strong>accurate and timely diagnosis<\/strong>. Patients have access to <strong>state-of-the-art imaging technologies<\/strong> that allow accurate assessment of the extent of the disease.<\/p>\n<p><!-- \/wp:paragraph --><\/p>\n<p><!-- wp:paragraph -->In addition, the Institute offers <strong>advanced and sophisticated laboratory investigations<\/strong>, including molecular and genomic analyses, which are critical for identifying biological features of cancer and guiding therapeutic decisions.<\/p>\n\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<div class=\"accordion group border-b border-white\/5\">\n\t\t\t<div class=\"flex items-center cursor-pointer group-hover:text-blue-light group-[.accordion--open]:text-red transition-colors\">\n\t\t\t\t<div class=\"rotate-90 text-blue-lighter group-[.accordion--open]:rotate-180 group-[.accordion--open]:text-red transition-all\">\n\t\t\t\t\t<svg width=\"18\" viewbox=\"0 0 500 500\" fill=\"currentColor\">\n\t\t\t\t\t\t<polygon points=\"250,60 100,400 400,400\"\/>\n\t\t\t\t\t<\/svg>\n\t\t\t\t<\/div>\n\t\t\t\t<h3 class=\"font-bold ml-5\">Minimally invasive surgical techniques and multidisciplinarity<\/h3>\n\t\t\t<\/div>\n\t\t\t<div class=\"accordion-content max-h-0 overflow-hidden transition-all\">\n\t\t\t\t<div class=\"pb-5 pl-[38px] pt-1\">\n\t\t\t\t\t<p>When indicated, surgery is performed with <strong>minimally invasive techniques<\/strong> (laparoscopic or thoracoscopic), which reduce operative trauma, promote faster recovery, and improve postoperative quality of life. Every treatment choice is defined within the GIC, ensuring a consistent and integrated approach.<\/p>\n\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<div class=\"accordion group border-b border-white\/5\">\n\t\t\t<div class=\"flex items-center cursor-pointer group-hover:text-blue-light group-[.accordion--open]:text-red transition-colors\">\n\t\t\t\t<div class=\"rotate-90 text-blue-lighter group-[.accordion--open]:rotate-180 group-[.accordion--open]:text-red transition-all\">\n\t\t\t\t\t<svg width=\"18\" viewbox=\"0 0 500 500\" fill=\"currentColor\">\n\t\t\t\t\t\t<polygon points=\"250,60 100,400 400,400\"\/>\n\t\t\t\t\t<\/svg>\n\t\t\t\t<\/div>\n\t\t\t\t<h3 class=\"font-bold ml-5\">Clinical research and access to trials<\/h3>\n\t\t\t<\/div>\n\t\t\t<div class=\"accordion-content max-h-0 overflow-hidden transition-all\">\n\t\t\t\t<div class=\"pb-5 pl-[38px] pt-1\">\n\t\t\t\t\t<h3 class=\"wp-block-heading\"><\/h3>\n<p><!-- \/wp:heading --><\/p>\n<p><!-- wp:paragraph -->As an IRCCS, the Candiolo Institute combines clinical practice with a <strong>strong vocation for scientific research.<\/strong> Patients can be evaluated for inclusion in active <strong>clinical trials<\/strong>, which represent a real chance to access <strong>innovative therapies<\/strong> not yet available in standard practice. Collaboration between care and research is a distinctive value that translates into <strong>concrete opportunities for the patient<\/strong>.<\/p>\n\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<div class=\"accordion group border-b border-white\/5\">\n\t\t\t<div class=\"flex items-center cursor-pointer group-hover:text-blue-light group-[.accordion--open]:text-red transition-colors\">\n\t\t\t\t<div class=\"rotate-90 text-blue-lighter group-[.accordion--open]:rotate-180 group-[.accordion--open]:text-red transition-all\">\n\t\t\t\t\t<svg width=\"18\" viewbox=\"0 0 500 500\" fill=\"currentColor\">\n\t\t\t\t\t\t<polygon points=\"250,60 100,400 400,400\"\/>\n\t\t\t\t\t<\/svg>\n\t\t\t\t<\/div>\n\t\t\t\t<h3 class=\"font-bold ml-5\">Care and support every step of the way<\/h3>\n\t\t\t<\/div>\n\t\t\t<div class=\"accordion-content max-h-0 overflow-hidden transition-all\">\n\t\t\t\t<div class=\"pb-5 pl-[38px] pt-1\">\n\t\t\t\t\t<p>The Interdisciplinary Care Group takes care of the person at every stage: from diagnosis to treatment to <strong>follow-up<\/strong>, with attention to <strong>nutritional support<\/strong>, <strong>psychological health<\/strong>, and <strong>reintegration into daily life<\/strong>. The organization of checkups, visits and treatment is designed to ensure <strong>continuity and serenity<\/strong>, always valuing the human dimension of care.<\/p>\n\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n\t<\/div>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5257","pathology","type-pathology","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Uterine fibroids - Istituto di Candiolo<\/title>\n<meta name=\"description\" content=\"Learn all about uterine fibroids: symptoms, gynecologic diagnosis, and conservative and surgical treatment options in Candiolo (Turin).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/irccs.com\/en\/pathology\/uterine-fibroids\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Uterine fibroids - 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